Our Services

We offer end-to-end process development services and technologies, covering fermentation, purification, and analysis, with capabilities for optimization and scale-up to meet both regulatory and economic requirements.
Our goal is to deliver cost-effective, robust, and scalable solutions tailored to your production needs.

Protein Engineering

We take cell line to develop your project from DNA to clone screening and selection. We have experience working with different types of expression system Ex. Pichia pastoris, E.coli

  • Transfection
  • Amplification
  • Clone screening
  • Clone selection

Protein Expression Development

We have established optimized cultivation methods for prokaryotes (such as E. coli), yeast, and mammalian cells, and provide fermentation process optimization services to help your strains achieve their best performance in the shortest possible time.

Our main equipment includes: Two 5L fermenters from New Brunswick Scientific (NBS), Integrated air and oxygen inlet lines
, Real-time monitoring of pH and dissolved oxygen, Fixed-angle and continuous centrifuges, CO₂ incubators, biosafety cabinets, and microscopes

  • Cell propagation in flasks, and Bioreactors
  • Clone selection based on productivity/stability
  • Media screening/optimization
  • Adaptation of cell lines
  • Bioreactor parameter optimization
  • Development of feed strategies
  • Process scale-up Scale-up/Technology transfer

Recovery & Purification Development

We develop column chromatography methods based on various principles and provide purification process optimization services to help you identify the optimal conditions for your purification process in the shortest possible time. Our main purification equipment includes AKTApurifier10, AKTA Primeplus, AKTA Piolt、fraction collectors、Lab TFF system、XK &BPG Column.

  • Develop new recovery/purification processes
  • Improve and trouble-shoot existing unit operations
  • Column chromatography — affinity, HIC, IEX, SEC
  • TFF, Ultrafiltration
  • Scale-up/Technology transfer

Cell bioactivity

Cells were purchased from Bioresource Collection and Research Center (BCRC)and American Type Culture Collection (ATCC).Key equipment includes Pressurized Clean Room, Optima/NIKON microscopies with digital camera, Laminar flow, CO2 incubator, Fluorescent activity assays

  • Cell Proliferation
  • Cell Migration
  • Boyden chamber
  • Transwell
  • FluoroBlok
  • Scratch wound healing
  • Tube Formation

Analytical Methods Development

Services and methods include testing for product/process related impurities and developing release and in-process assays in support of microbial fermentation, cell culture and purification development.

  • BCA /Bradford protein assays
  • A280 protein determination
  • pH
  • Conductivity
  • ELISA assays
  • HPLC-affinity, IEX, HIC, SEC, RP-HPLC
  • SDS-PAGE analysis
  • IEF analysis
  • Western blot analysis